OTF-SOFT | Torso

OTF-SOFT | Torso

OTF-SOFT, Omega-3 Marine Triglycerides Capsules are polyunsaturated fatty acids (PUFAs). involved in human physiology includes Eicosapentaenoic acid (EPA), and Docosahexaenoic acid (DHA). Omega-3 fatty acids play a critical role in metabolism and cellular function, possess potent antiarrhythmic effects, form the structures of the cell membranes and also serve as energy source. They form eicosanoids which are important signaling molecules with wide-ranging functions in the body cardiovascular, pulmonary, immune and endocrine systems. DHA tends to exist in high concentrations in the retina and brain.

Composition

Omega 3 Marine Triglycerides — EPA 180 mg, DHA 120 mg

Mode of Action

Omega-3 fatty acids mediate anti-inflammatory effects and increased levels of EPA or DHA has shown to decrease the levels of PGE2 and 4 series-LT. Eicosapentaenoic acids compete with constitutive levels of arachidonic acid in cell membranes for the same desaturation enzymes and produce 3-series prostaglandins and thromboxanes, and 5-series leukotrienes which have low pro-inflammatory potential. The alteration in leukotriene biosynthesis due to higher concentration of omega-3 fatty acids compared to arachidonic acid underlies the anti-inflammatory effects. EPA and DHA also give rise to resolvins and related lipid signaling molecules such as protectins via cyclooxygenase and lipoxygenase pathways, which have anti-inflammatory effects. They inhibit transendothelial migration of neutrophils and inhibit TNF and IL-1β production.

Indications

Omega-3 fatty acids reduce inflammation, proteinuria and slow the progression of kidney disease. This can further help prevent further decline of kidney function in patients with CKD, and reduce risk of developing end-stage renal disease.

Dosage

1–2 Capsules / Day.

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OTF-SOFT | Torso

OTF-SOFT, Omega-3 Marine Triglycerides Capsules are polyunsaturated fatty acids (PUFAs). involved in human physiology includes Eicosapentaenoic acid (EPA), and Docosahexaenoic acid (DHA). Omega-3 fatty acids…

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